Searchable abstracts of presentations at key conferences in endocrinology

ea0081p601 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Isoflavones genistein and daidzein enhance the expression of Slc2a4 mRNA and GLUT4 protein in adipocytes

Rego Gregorio Karen Cristina , Pancera Laurindo Caroline , Fabres Machado Ubiratan

According to the world Health Organization, about 422 million people worldwide have diabetes mellitus (DM), and this number is growing rapidly. DM, mainly type 2, is associated with insulin resistance, which involves reduced expression of glucose transporter GLUT4 (Slc2a4 gene). It is known that estrogen can modulate glycemic homeostasis and seems to involve changes in the Slc2a4/GLUT4 expression. There has been an increased interest in plant-derived phytoest...